Publicaciones

1.    de Vasconcelos Junior AA, Tirado-Vélez JM, Martín-Galiano AJ, Megias D, Ferrándiz MJ, Hernández P, Amblar M, de la Campa AG. StaR is a positive regulator of topoisomerase I activity involved in supercoiling maintenance in Streptococcus pneumoniae. Int J Mol Sci. 2023; 24:5973. doi: 10.3390/ijms24065973. PMID: 36983048; PMCID: PMC10053502.

2.    García-López M, Megias D, Ferrándiz MJ, de la Campa AG. The balance between gyrase and topoisomerase I activities determines levels of supercoiling, nucleoid compaction, and viability in bacteria. Front Microbiol. 2023; 11;1094692. doi: 10.3389/fmicb.2022.1094692. PMID: 36713152; PMCID: PMC9875019.

3.    Amblar M, Zaballos A, de la Campa AG. Role of PatAB transporter in efflux of levofloxacin in Streptococcus pneumoniae. Antibiotics. 2022; 17:1837. doi: 10.3390/antibiotics11121837. PMID: 36551495; PMCID: PMC9774293.

4.    Ferrándiz M-J, Hernández P, de la Campa AG. Genome-wide proximity between RNA polymerase and DNA topoisomerase I supports transcription in Streptococcus pneumoniae. PLoS Genet. 2021; 17:e1009542. doi: 10.1371/journal.pgen.1009542. PMID: 33930020; PMCID: PMC8115823.

5.    Acebo P, Herranz C, Bernal-Espenberger L, Gómez-Sanz A, Terron MC, Luque D and Amblar M. A small non-coding RNA modulates expression of Pilus-1 type in Streptococcus pneumoniae. Microorganisms. 2021; 9:1883. doi: 10.3390/microorganisms9091883; PMID: 34576778; PMCID: PMC8465756.

6.    García MT, Valenzuela MV, Ferrándiz MJ, de la Campa AG. Reactive oxygen species production is a major factor directing the post-antibiotic effect of fluoroquinolones in Streptococcus pneumoniae. Antimicrob Agents Chemother. 2019; 63:e00737-19. doi: 10.1128/AAC.00737-19. PMID: 31160286; PMCID: PMC6658797.

7.    Ferrándiz MJ, Carreño D, Ayora S, de la Campa AG. HU of Streptococcus pneumoniae is essential for the preservation of DNA supercoiling. Front Microbiol. 2018; 9:493. doi: 10.3389/fmicb.2018.00493. PMID: 29662473; PMCID: PMC5890176.

8.    García MT, Carreño D, Tirado-Vélez JM, Ferrándiz MJ, Rodrigues L, Gracia B, Amblar M, Ainsa JA, de la Campa AG. Boldine-derived alkaloids inhibit the activity of DNA topoisomerase I and growth of Mycobacterium tuberculosis. Front Microbiol. 2018; 9:493. doi: 10.3389/fmicb.2018.01659. PMID: 30087665; PMCID: PMC6066988.

9.    Brito L, Wilton J, Ferrándiz MJ, Gómez-Sanz A, de la Campa AG, Amblar M.  Absence of tmRNA has a protective effect against fluoroquinolones in Streptococcus pneumoniae. Front Microbiol. 2017; 7:2164. doi: 10.3389/fmicb.2016.02164. PMID: 28119681; PMCID: PMC5222879.

10.    Martín-Galiano AJ, Ferrándiz MJ, de la Campa AG.  Bridging chromosomal architecture and pathophysiology of Streptococcus pneumoniae. Genome Biol Evol. 2017; 9:350-361. doi: 10.1093/gbe/evw299. PMID: 28158485; PMCID: PMC5381641.

11.    Alvarado M, Martín-Galiano AJ, Ferrándiz MJ, Zaballos A, de la Campa AG. Upregulation of the PatAB transporter confers fluoroquinolone resistance to Streptococcus pseudopneumoniae. Front Microbiol. 2017; 8:2074. doi: 10.3389/fmicb.2017.02074. PMID: 29123510; PMCID: PMC5662624.

12.    Domenech A, Moreno J, Ardanuy C, Liñares J, de la Campa AG, Martin-Galiano AJ. A novel typing method for Streptococcus pneumoniae using selected surface proteins. Front Microbiol. 2016; 31;7:420. doi: 10.3389/fmicb.2016.00420. PMID: 27064593; PMCID: PMC4815138.

13.    Ferrándiz MJ, Martín-Galiano AJ, Arnanz C, Camacho-Soguero I, Tirado-Vélez JM, de la Campa AG.  An increase in negative supercoiling in bacteria reveals topology-reacting gene clusters and a homeostatic response mediated by the DNA topoisomerase I gene. Nucl Acids Res. 2016; 44:7292-7303. doi: 10.1093/nar/gkw602. PMID: 27378778; PMCID: PMC5009749.

14.    Ferrándiz MJ, Martín-Galiano AJ, Arnanz C, Zimmerman T, de la Campa AG. Reactive oxygen species contribute to the bactericidal effects of the fluoroquinolone moxifloxacin in Streptococcus pneumoniae. Antimicrob Agents Chemother. 2016; 60:409-417. doi: 10.1128/AAC.02299-15. PMID: 26525786; PMCID: PMC4704168.

15.    Ferrándiz MJ, de la Campa AG. The fluoroquinolone levofloxacin triggers the transcriptional activation of iron transport genes that contributes to cell death in Streptococcus pneumoniae. Antimicrob Agents Chemother. 2014; 58:247-257. doi: 10.1128/AAC.01706-13. PMID: 24145547; PMCID: PMC3910755.


Actualizado a 13/06/2023