Publicaciones

​A continuación se referencian las 15 publicaciones más destacadas del grupo de investigación de los últimos 5 años.

Cytotoxic cell populations developed during treatment with tyrosine kinase inhibitors protect autologous CD4+ T cells from HIV-1 infection. Vigón L, Rodríguez-Mora S, Luna A, Sandonís V, Mateos E, Bautista G, Steegmann JL, Climent N, Plana M, Pérez-Romero P, de Ory F, Alcamí J, García-Gutierrez V, Planelles V, López-Huertas MR, Coiras M.Vigón L, et al. Biochem Pharmacol. 2020 Aug 20;182:114203. doi: 10.1016/j.bcp.2020.114203. Online ahead of print.Biochem Pharmacol. 2020. PMID: 32828803

Role of Neutralizing Antibodies in CMV Infection: Implications for New Therapeutic Approaches. Sandonís V, García-Ríos E, McConnell MJ, Pérez-Romero P.Sandonís V, et al. Trends Microbiol. 2020 Nov;28(11):900-912. doi: 10.1016/j.tim.2020.04.003. Epub 2020 May 21.Trends Microbiol. 2020. PMID: 32448762 Review.   

Improvement in detecting cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance using next generation sequencing.  López-Aladid R, Guiu A, Mosquera MM, López-Medrano F, Cofán F, Linares L, Torre-Cisneros J, Vidal E, Moreno A, Aguado JM, Cordero E, Martin-Gandul C, Carratalá J, Sabé N, Niubó J, Cervera C, Capón A, Cervilla A, Santos M, Bodro M, Muñoz P, Fariñas MC, Antón A, Aranzamendi M, Montejo M, Pérez-Romero P, Len O, Marcos MÁ.López-Aladid R, et al. PLoS One. 2019 Jul 18;14(7):e0219701. doi: 10.1371/journal.pone.0219701. eCollection 2019.PLoS One. 2019. PMID: 31318908 Free PMC article. Clinical Trial.

Humoral response to natural influenza infection in solid organ transplant recipients. Hirzel C, Ferreira VH, L'Huillier AG, Hoschler K, Cordero E, Limaye AP, Englund JA, Reid G, Humar A, Kumar D; Influenza in Transplant Study Group.Hirzel C, et al. Am J Transplant. 2019 Aug;19(8):2318-2328. doi: 10.1111/ajt.15296. Epub 2019 Mar 18.Am J Transplant. 2019. PMID: 30748090 Clinical Trial.

Going beyond serology for stratifying the risk of CMV infection in transplant recipients.  Navarro D, Fernández-Ruiz M, Aguado JM, Sandonís V, Pérez-Romero P.Navarro D, et al. Rev Med Virol. 2019 Jan;29(1):e2017. doi: 10.1002/rmv.2017. Epub 2018 Oct 25.Rev Med Virol. 2019. PMID: 30358016 Review.

A 5-Year Prospective Multicenter Evaluation of Influenza Infection in Transplant Recipients.  Kumar D, Ferreira VH, Blumberg E, Silveira F, Cordero E, Perez-Romero P, Aydillo T, Danziger-Isakov L, Limaye AP, Carratala J, Munoz P, Montejo M, Lopez-Medrano F, Farinas MC, Gavalda J, Moreno A, Levi M, Fortun J, Torre-Cisneros J, Englund JA, Natori Y, Husain S, Reid G, Sharma TS, Humar A.Kumar D, et al. Clin Infect Dis. 2018 Oct 15;67(9):1322-1329. doi: 10.1093/cid/ciy294.Clin Infect Dis. 2018. PMID: 29635437 Clinical Trial.

Impact of pretransplant CMV-specific T-cell immune response in the control of CMV infection after solid organ transplantation: a prospective cohort study.  Molina-Ortega A, Martín-Gandul C, Mena-Romo JD, Rodríguez-Hernández MJ, Suñer M, Bernal C, Sánchez M, Sánchez-Céspedes J, Pérez Romero P, Cordero E.Molina-Ortega A, et al. Clin Microbiol Infect. 2019 Jun;25(6):753-758. doi: 10.1016/j.cmi.2018.09.019. Epub 2018 Oct 5.Clin Microbiol Infect. 2019. PMID: 30292792 Clinical Trial.

Kinetic of the CMV-specific T-cell immune response and CMV infection in CMV-seropositive kidney transplant recipients receiving rabbit anti-thymocyte globulin induction therapy: A pilot study.  Martín-Gandul C, Pérez-Romero P, Mena-Romo D, Molina-Ortega A, González-Roncero FM, Suñer M, Bernal G, Cordero E; Spanish Network for Research in Infectious Diseases (REIPI).Martín-Gandul C, et al. Transpl Infect Dis. 2018 Jun;20(3):e12883. doi: 10.1111/tid.12883. Epub 2018 Apr 16.Transpl Infect Dis. 2018. PMID: 29570917 Clinical Trial.

CMV-specific T-cell immunity in solid organ transplant recipients at low risk of CMV infection. Chronology and applicability in preemptive therapy. Mena-Romo JD, Pérez Romero P, Martín-Gandul C, Gentil MÁ, Suárez-Artacho G, Lage E, Sánchez M, Cordero E.Mena-Romo JD, et al. J Infect. 2017 Oct;75(4):336-345. doi: 10.1016/j.jinf.2017.05.020. Epub 2017 Jun 13.J Infect. 2017. PMID: 28599954 Clinical Trial.

Two Doses of Inactivated Influenza Vaccine Improve Immune Response in Solid Organ Transplant Recipients: Results of TRANSGRIPE 1-2, a Randomized Controlled Clinical Trial. Cordero E, Roca-Oporto C, Bulnes-Ramos A, Aydillo T, Gavaldà J, Moreno A, Torre-Cisneros J, Montejo JM, Fortun J, Muñoz P, Sabé N, Fariñas MC, Blanes-Julia M, López-Medrano F, Suárez-Benjumea A, Martinez-Atienza J, Rosso-Fernández C, Pérez-Romero P. Clin Infect Dis. 2017 Apr 1;64(7):829-838. doi: 10.1093/cid/ciw855.Clin Infect Dis. 2017. PMID: 28362949 Clinical Trial.

Detection of cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance.  López-Aladid R, Guiu A, Sanclemente G, López-Medrano F, Cofán F, Mosquera MM, Torre-Cisneros J, Vidal E, Moreno A, Aguado JM, Cordero E, Martin-Gandul C, Pérez-Romero P, Carratalá J, Sabé N, Niubó J, Cervera C, Cervilla A, Bodro M, Muñoz P, Fariñas C, Codina MG, Aranzamendi M, Montejo M, Len O, Marcos MA; Group for Study of Infection in Transplantation of the Spanish Society of Infectious Diseases Clinical Microbiology GESITRA-SEIMC Spanish Network for Research in Infectious.López-Aladid R, et al. J Clin Virol. 2017 May;90:57-63. doi: 10.1016/j.jcv.2017.03.014. Epub 2017 Mar 21.J Clin Virol. 2017. PMID: 28359845 Clinical Trial.

Prevention strategies differentially modulate the impact of cytomegalovirus replication on CD8(+) T-cell differentiation in high-risk solid organ transplant patients.  Cantisán S, Páez-Vega A, Pérez-Romero P, Montejo M, Cordero E, Gracia-Ahufinger I, Martín-Gandul C, Maruri N, Aguado R, Solana R, Torre-Cisneros J; Spanish Network for Research in Infectious Diseases (REIPI).Cantisán S, et al. Antiviral Res. 2016 Aug;132:244-51. doi: 10.1016/j.antiviral.2016.06.012. Epub 2016 Jul 1.Antiviral Res. 2016. PMID: 27378225 Clinical Trial.

Applying lessons learned from cytomegalovirus infection in transplant patients to vaccine design. Blanco-Lobo P, Bulnes-Ramos Á, McConnell MJ, Navarro D, Pérez-Romero P.Blanco-Lobo P, et al. Drug Discov Today. 2016 Apr;21(4):674-81. doi: 10.1016/j.drudis.2016.03.005. Epub 2016 Mar 11.Drug Discov Today. 2016. PMID: 26976691 Review.

Use of antibodies neutralizing epithelial cell infection to diagnose patients at risk for CMV Disease after transplantation. Blanco-Lobo P, Cordero E, Martín-Gandul C, Gentil MA, Suárez-Artacho G, Sobrino M, Aznar J, Pérez-Romero P.Blanco-Lobo P, et al. J Infect. 2016 May;72(5):597-607. doi: 10.1016/j.jinf.2016.02.008. Epub 2016 Feb 24.J Infect. 2016. PMID: 26920791 Clinical Trial.

Influenza vaccination during the first 6 months after solid organ transplantation is efficacious and safe. Pérez-Romero P, Bulnes-Ramos A, Torre-Cisneros J, Gavaldá J, Aydillo TA, Moreno A, Montejo M, Fariñas MC, Carratalá J, Muñoz P, Blanes M, Fortún J, Suárez-Benjumea A, López-Medrano F, Barranco JL, Peghin M, Roca C, Lara R, Cordero E; Influenza Vaccine in Solid Organ Transplant Recipient Study Group, Spanish Network of Research in Infectious Diseases (REIPI-GESITRA); Influenza Vaccine in Solid Organ Transplant Recipient Study Group Spanish Network of Research in Infectious Diseases REIPI-GESITRA.Pérez-Romero P, et al. Clin Microbiol Infect. 2015 Nov;21(11):1040.e11-8. doi: 10.1016/j.cmi.2015.07.014. Epub 2015 Jul 29.Clin Microbiol Infect. 2015. PMID: 26232537 Clinical Trial.