1: Rossi SA, de Oliveira HC, Agreda-Mellon D, Lucio J, Mendes-Giannini MJS, García-Cambero JP, Zaragoza O. Identification of Off-Patent Drugs That Show Synergism with Amphotericin B or That Present Antifungal Action against
Cryptococcus neoformans and
Candida spp. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e01921-19. doi:
10.1128/AAC.01921-19. PMID:
31988099; PMCID: PMC7179310.
2: de Oliveira HC, Monteiro MC, Rossi SA, Pemán J, Ruiz-Gaitán A, Mendes- Giannini MJS, Mellado E, Zaragoza O. Identification of Off-Patent Compounds That Present Antifungal Activity Against the Emerging Fungal Pathogen
Candida auris. Front Cell Infect Microbiol. 2019 Apr 2;9:83. doi:
10.3389/fcimb.2019.00083. PMID:
31001487; PMCID: PMC6454888.
3: Trevijano-Contador N, de Oliveira HC, García-Rodas R, Rossi SA, Llorente I, Zaballos Á, Janbon G, Ariño J, Zaragoza Ó.
Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals. PLoS Pathog. 2018 May 18;14(5):e1007007. doi:
10.1371/journal.ppat.1007007. PMID:
29775477; PMCID: PMC5959073.
4: Rueda C, Puig-Asensio M, Guinea J, Almirante B, Cuenca-Estrella M, Zaragoza O; CANDIPOP Project from GEIH-GEMICOMED (SEIMC) and REIPI. Evaluation of the possible influence of trailing and paradoxical effects on the clinical outcome of patients with candidemia. Clin Microbiol Infect. 2017 Jan;23(1):49.e1-49.e8. doi:
10.1016/j.cmi.2016.09.016. PMID:
27677697.
5: Mesa-Arango AC, Rueda C, Román E, Quintin J, Terrón MC, Luque D, Netea MG, Pla J, Zaragoza O. Cell Wall Changes in Amphotericin B-Resistant Strains from
Candida tropicalis and Relationship with the Immune Responses Elicited by the Host. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2326-35. doi:
10.1128/AAC.02681-15. PMID:
26833156; PMCID: PMC4808153.
6: García-Barbazán I, Trevijano-Contador N, Rueda C, de Andrés B, Pérez-Tavárez R, Herrero-Fernández I, Gaspar ML, Zaragoza O. The formation of titan cells in
Cryptococcus neoformans depends on the mouse strain and correlates with induction of Th2-type responses. Cell Microbiol. 2016 Jan;18(1):111-24. doi:
10.1111/cmi.12488. Epub 2015 Sep 6. PMID:
26243235.
7: Trevijano-Contador N, Herrero-Fernández I, García-Barbazán I, Scorzoni L, Rueda C, Rossi SA, García-Rodas R, Zaragoza O.
Cryptococcus neoformans induces antimicrobial responses and behaves as a facultative intracellular pathogen in the non mammalian model
Galleria mellonella. Virulence. 2015;6(1):66-74. doi:
10.4161/21505594.2014.986412. PMID:
25531532; PMCID: PMC4603429.
8: Mesa-Arango AC, Trevijano-Contador N, Román E, Sánchez-Fresneda R, Casas C, Herrero E, Argüelles JC, Pla J, Cuenca-Estrella M, Zaragoza O. The production of reactive oxygen species is a universal action mechanism of Amphotericin B against pathogenic yeasts and contributes to the fungicidal effect of this drug. Antimicrob Agents Chemother. 2014 Nov;58(11):6627-38. doi: 10.1128/AAC.03570-14. Epub 2014 Aug 25. PMID:
25155595; PMCID: PMC4249417.
9: García-Rodas R, Cordero RJ, Trevijano-Contador N, Janbon G, Moyrand F, Casadevall A, Zaragoza O. Capsule growth in
Cryptococcus neoformans is coordinated with cell cycle progression. mBio. 2014 Jun 17;5(3):e00945-14. doi:
10.1128/mBio.00945-14. PMID:
24939886; PMCID: PMC4056547.
10: Rueda C, Cuenca-Estrella M, Zaragoza O. Paradoxical growth of
Candida albicans in the presence of caspofungin is associated with multiple cell wall rearrangements and decreased virulence. Antimicrob Agents Chemother. 2014;58(2):1071-83. doi:
10.1128/AAC.00946-13. Epub 2013 Dec 2. PMID:
24295973; PMCID: PMC3910852.
11: Puig-Asensio M, Padilla B, Garnacho-Montero J, Zaragoza O, Aguado JM, Zaragoza R, Montejo M, Muñoz P, Ruiz-Camps I, Cuenca-Estrella M, Almirante B; CANDIPOP Project; GEIH-GEMICOMED (SEIMC); REIPI. Epidemiology and predictive factors for early and late mortality in
Candida bloodstream infections: a population-based surveillance in Spain. Clin Microbiol Infect. 2014 Apr;20(4):O245-54. doi:
10.1111/1469-0691.12380. Epub 2013 Oct 11. PMID:
24125548.
12: García-Rodas R, González-Camacho F, Rodríguez-Tudela JL, Cuenca-Estrella M, Zaragoza O. The interaction between
Candida krusei and murine macrophages results in multiple outcomes, including intracellular survival and escape from killing. Infect Immun. 2011 Jun;79(6):2136-44. doi:
10.1128/IAI.00044-11. Epub 2011 Mar 21. PMID:
21422181; PMCID: PMC3125833.
13: Zaragoza O, García-Rodas R, Nosanchuk JD, Cuenca-Estrella M, Rodríguez- Tudela JL, Casadevall A. Fungal cell gigantism during mammalian infection. PLoS Pathog. 2010 Jun 17;6(6):e1000945. doi:
10.1371/journal.ppat.1000945. PMID:
20585557; PMCID: PMC2887474.
14: Trevijano-Contador N, Pianalto KM, Nichols CB, Zaragoza O, Alspaugh JA, Pirofski LA. Human IgM Inhibits the Formation of Titan-Like Cells in
Cryptococcus neoformans. Infect Immun. 2020 Mar 23;88(4):e00046-20. doi:
10.1128/IAI.00046-20. PMID:
31988178; PMCID: PMC7093138.
15: Velasco-de-Andrés M, Català C, Casadó-Llombart S, Simões I, Zaragoza O, Carreras E, Lozano F. The lymphocyte scavenger receptor CD5 plays a nonredundant role in fungal infection. Cell Mol Immunol. 2020 Apr 24. doi:
10.1038/s41423-020-0434-7. Epub ahead of print. PMID:
32332900.