Publicaciones

  1. De la Vieja A* and Santisteban P*. Iodide role in physiology and cancer. Invited review in Endocrine-Related Cancer. 2017. Submitted (* Co-corresponding authors).

  2. Pérez-Fernández L*, De la Vieja A*, Riesco-Eizaguirre G, Zafón C, Galofré JC, y los miembros del grupo español para el estudio de BRAF de la SEEN. Prognostic value of BRAF oncogene in Papillary Thyroid Cancer: A multicentric analysis of Spanish population. 2017. Submitted (*Co-first authors)

  3. Chocarro-Calvo A, García-Martínez JM, Gutiérrez-Salmerón M, De la Vieja A y García-Jiménez C. Role of AMP-activated protein kinase (AMPK) in colon cancer. 2017. Submitted.

  4. Belmar-López C, Crespo-Barreda A, Vassaux G, Burnet J, Quintanilla M, Ramón y Cajal S, Hernández-Lasa J De la Vieja A, and Martín-Duque P. Simultaneous Tracking of Mesenchymal Stem Cells on Different Pathologies by Non-Invasive Imaging Techniques. 2017. Submitted.

  5. Koumarianou P, De la Vieja A* and Santisteban P*. NIS is basolateraly sorted by AP-1A and AP-1B clathrin adaptors in MDCK cells (* Co-corresponding authors). 2017. Submitted

  6. Gutiérrez-Salmerón M, Chocarro-Calvo A, García-Martínez JM, de la Vieja A, García-Jiménez C. Epidemiological bases and molecular mechanisms linking obesity, diabetes, and cancer. Endocrinol Diabetes Nutr. 2017 Feb; 64(2):109-117. (https://www.ncbi.nlm.nih.gov/pubmed/28440775)

    doi:10.1016/j.endinu.2016.10.005

  7. García-Jiménez C, Gutiérrez-Salmerón M, Chocarro-Calvo A, García-Martínez JM, Castaño A, De la Vieja A. From obesity to diabetes and cancer: epidemiological links and role of therapies. Br J Cancer. 2016 Mar 29; 114(7):716-22. (https://www.ncbi.nlm.nih.gov/pubmed/26908326)

    doi: 10.1038/bjc.2016.37

  8. Leoni SG, Sastre-Perona A, De la Vieja A, Santisteban P. Selenium Increases Thyroid-Stimulating Hormone-Induced Sodium/Iodide Symporter Expression Through Thioredoxin/Apurinic/Apyrimidinic Endonuclease 1-Dependent Regulation of Paired Box 8 Binding Activity. Antioxid Redox Signal. 2016 May 20; 24(15):855-66. (https://www.ncbi.nlm.nih.gov/pubmed/26908326)

    doi: 10.1089/ars.2014.6228

  9. García-Martínez JM, Chocarro-Calvo A, De la Vieja A, García-Jiménez C. Insulin drives glucose-dependent insulinotropic peptide expression via glucose-dependent regulation of FoxO1 and LEF1/β-catenin. Biochim Biophys Acta. 2014 Nov; 1839(11):1141-50. (https://www.ncbi.nlm.nih.gov/pubmed/25091498)

    doi:10.1016/j.bbagrm.2014.07.020

  10. Riesco-Eizaguirre G, Leoni SG, Mendiola M, Estévez-Cebrero MA, Gallego MI, Redondo A, Hardisson D, Santisteban P, De la Vieja A. NIS mediates iodide uptake in the female reproductive tract and is a poor prognostic factor in ovarian cancer. J Clin Endocrinol Metab. 2014 Jul; 99(7):E1199-208. (https://www.ncbi.nlm.nih.gov/pubmed/24708099)

    doi: 10.1210/jc.2013-4249

  11. Donnay S, Arena J, Lucas A, Velasco I, Ares S; Working Group on Disorders Related to Iodine Deficiency and Thyroid Dysfunction of the Spanish Society of Endocrinology and Nutrition.. Iodine supplementation during pregnancy and lactation. Position statement of the working group on disorders related to iodine deficiency and thyroid dysfunction of the Spanish Society of Endocrinology and Nutrition. Endocrinol Nutr. 2014 Jan; 61(1):27-34. (https://www.ncbi.nlm.nih.gov/pubmed/24035326)

    doi:10.1016/j.endonu.2013.05.004

  12. García-Jiménez C, García-Martínez JM, Chocarro-Calvo A, De la Vieja A. A new link between diabetes and cancer: enhanced WNT/β-catenin signaling by high glucose. J Mol Endocrinol. 2013 Dec 19; 52(1):R51-66. Print 2014 Feb. (https://www.ncbi.nlm.nih.gov/pubmed/24049067)

    doi: 10.1530/JME-13-0152

  13. Vila L, Velasco I, González S, Morales F, Sánchez E, Lailla JM, Martinez-Astorquiza T, Puig-Domingo M; Grupo de Trabajo de Trastornos por Deficiencia de Yodo y Disfunción Tiroidea de la Sociedad Española de Endocrinología y Nutrición. Detection of thyroid dysfunction in pregnant women: universal screening is justified. Endocrinol Nutr. 2012 Nov; 59(9):547-60. (https://www.ncbi.nlm.nih.gov/pubmed/23099114.

    doi: 10.1016/j.endonu.2012.06.014

  14. Vila L, Velasco I, González S, Morales F, Sánchez E, Lailla JM, Martínez-Astorquiza T, Puig-Domingo M; el Grupo de Trabajo de Trastornos por Deficiencia de Yodo y Disfunción Tiroidea de la Sociedad Española de Endocrinología y Nutrición.; Sociedad Española de Ginecología y Obstetricia. [Detection of thyroid dysfunction in pregnant women: universal screening is justified]. Med Clin (Barc). 2012 Nov 3; 139(11):509.e1-509.e11.   (https://www.ncbi.nlm.nih.gov/pubmed/22981085)

    doi:10.1016/j.medcli.2012.06.004

  15. Donnay S, Vila L; Task force on disorders related to iodine deficiency and thyroid dysfunction. Eradication of iodine deficiency in Spain. Close, but not there yet. Endocrinol Nutr. 2012 Oct; 59(8):471-3. (https://www.ncbi.nlm.nih.gov/pubmed/22841779)

    doi: 10.1016/j.endoen.2012.05.003

  16. Leoni SG, Kimura ET, Santisteban P, De la Vieja A. Regulation of thyroid oxidative state by thioredoxin reductase has a crucial role in thyroid responses to iodide excess. Mol Endocrinol. 2011 Nov; 25(11):1924-35. (https://www.ncbi.nlm.nih.gov/pubmed/21903721)

    doi: 10.1210/me.2011-0038

  17. Riesco-Eizaguirre G, De la Vieja A, Rodríguez I, Miranda S, Martín-Duque P, Vassaux G, Santisteban P. Telomerase-driven expression of the sodium iodide symporter (NIS) for in vivo radioiodide treatment of cancer: a new broad-spectrum NIS-mediated antitumor approach. J Clin Endocrinol Metab. 2011 Sep; 96(9):E1435-43. (https://www.ncbi.nlm.nih.gov/pubmed/21697253)

    doi: 10.1210/jc.2010-2373

  18. Merron A, Baril P, Martín-Duque P, de la Vieja A, Tran L, Briat A, Harrington KJ, McNeish IA, Vassaux G. Assessment of the Na/I symporter as a reporter gene to visualize oncolytic adenovirus propagation in peritoneal tumours. Eur J Nucl Med Mol Imaging. 2010 Jul; 37(7):1377-85.. (https://www.ncbi.nlm.nih.gov/pubmed/20140612)

    doi:10.1007/s00259-009-1379-3

  19. Riesco-Eizaguirre G, Rodríguez I, De la Vieja A, Costamagna E, Carrasco N, Nistal M, Santisteban P. The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer. Cancer Res. 2009 Nov 1; 69(21):8317-25. (https://www.ncbi.nlm.nih.gov/pubmed/19861538)

    doi:10.1158/0008-5472.CAN-09-1248

  20. Montiel-Equihua CA, Martín-Duque P, de la Vieja A, Quintanilla M, Burnet J, Vassaux G, Lemoine NR. Targeting sodium/iodide symporter gene expression for estrogen-regulated imaging and therapy in breast cancer. Cancer Gene Ther. 2008 Jul; 15(7):465-73.  (https://www.ncbi.nlm.nih.gov/pubmed/18421306)

    doi:10.1038/cgt.2008.6

  21. Reed-Tsur MD, De la Vieja A, Ginter CS, Carrasco N. Molecular characterization of V59E NIS, a Na+/Isymporter mutant that causes congenital Itransport defect. Endocrinology. 2008 Jun; 149(6):3077-84. (https://www.ncbi.nlm.nih.gov/pubmed/18339708)

    doi:10.1210/en.2008-0027

  22. De la Vieja A, Reed MD, Ginter CS, Carrasco N. Amino acid residues in transmembrane segment IX of the Na+/Isymporter play a role in its Na+ dependence and are critical for transport activity. J Biol Chem. 2007 Aug 31; 282(35):25290-8. (https://www.ncbi.nlm.nih.gov/pubmed/17606623)

    doi:10.1074/jbc.M700147200